Detalhe da pesquisa
1.
An aged immune system drives senescence and ageing of solid organs.
Nature
; 594(7861): 100-105, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33981041
2.
Adenoviral gene transfer of a single-chain IL-23 induces psoriatic arthritis-like symptoms in NOD mice.
FASEB J
; 33(8): 9505-9515, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31170010
3.
Failure to repair endogenous DNA damage in ß-cells causes adult-onset diabetes in mice.
Aging Biol
; 1(1)2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38124711
4.
Loss of DNA repair mechanisms in cardiac myocytes induce dilated cardiomyopathy.
Aging Cell
; 22(4): e13782, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36734200
5.
Novel small molecule inhibition of IKK/NF-κB activation reduces markers of senescence and improves healthspan in mouse models of aging.
Aging Cell
; 20(12): e13486, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34734460
6.
Mesenchymal stem cell-derived extracellular vesicles reduce senescence and extend health span in mouse models of aging.
Aging Cell
; 20(4): e13337, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33728821
7.
Development of an IGF1R longevity variant mouse line using CRISPR/Cas9 genome editing.
Trends Biomed Res
; 3(1)2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37113577
8.
Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice.
Aging Cell
; 19(3): e13094, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31981461
9.
ATM is a key driver of NF-κB-dependent DNA-damage-induced senescence, stem cell dysfunction and aging.
Aging (Albany NY)
; 12(6): 4688-4710, 2020 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32201398
10.
Mouse Models of Accelerated Cellular Senescence.
Methods Mol Biol
; 1896: 203-230, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30474850
11.
Fisetin is a senotherapeutic that extends health and lifespan.
EBioMedicine
; 36: 18-28, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-30279143